Opta has made Manchester City big favourites to retain the Premier League title.
This follows their 4-0 win at Brighton on Thursday, two days after Arsenal crushed Chelsea 5-0 at the Emirates.
Liverpool also lost 2-0 to Everton in the Merseyside Derby on Wednesday.
Following the completion of these matches, Opta's title predictor is now up to 71.1% in favour of City winning the Premier League.
Arsenal has a 27% chance of winning it and Liverpool a 1.6% chance.
The next round of games will see Liverpool travel to West Ham, while Arsenal clash with Tottenham.
City are away to Nottingham Forest on Sunday.
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