Manchester United are also considering a move for Barcelona star Marcos Alonso as they seek to bring in an emergency option at left-back.
United hope to bring in a new left-back before next week's transfer deadline after losing Luke Shaw to injury. The England international is expected to be out until November with Tyrell Malacia also still sidelined.
Inquiries have been made over the availability of Chelsea's Marc Cucurella and Sergio Reguilon of Tottenham but according to the Daily Telegraph, United have also asked about Alonso.
The 32-year-old ended his six-year spell at Chelsea last summer to join Barcelona, starting 11 La Liga matches in their title-winning campaign last season.
19-year-old Alejandro Balde has also been preferred by Xavi in Barcelona's opening two games of the new season.
United are also exploring a move for Cucurella, just a year on from his £60m move from Brighton.
The Spaniard endured a difficult first season at Stamford Bridge and has not featured under Mauricio Pochettino this term with Ben Chilwell the club's first-choice option with Ian Maatsen in reserve with Levi Colwill also an option at left-back.
It remains to be seen however whether Chelsea will sanction a deal that could see them aid a direct rival for Champions League football.
Regulion is another option under consideration with Tottenham open to allowing the 26-year-old to leave the club.
United were interested in signing him back in 2020 when Spurs struck a £27m deal with Real Madrid. The left-back returned to Spain on loan last season, spending the season with Real Madrid.
With both Shaw and Malacia unavailable, Diogo Dalot shifted over to a left-back role as United came from behind to beat Nottingham Forest 3-2 at Old Trafford on Saturday.
Having also allowed Brandon Williams to join Ipswich on loan, viable options on the left are in short supply.
20-year-old Alvaro Fernandez was an unused substitute against Forest but will hope to force his way into the side after an impressive loan spell at Preston last season.
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