Real Madrid who are the defending champions of the Champions League were drawn against Ajax in what is expected to be a tough encounter.
It can be said that Barcelona were given the opponents that should not be a problem for them as they face French side Lyon in the round of 16.
Also in the round of 16, three Premier League clubs who are Manchester City, Liverpool and Tottenham will be facing German clubs.
But in this report, we will be taking a look at some big games in the 2018/19 Champions League knock out stage to watch out for.
Ajax v Real Madrid
Throughout all their group stage games, Dutch club Ajax did not lose any match, and they will be facing the defending champions Real Madrid who lost two games before they qualified as leaders in group G.
Ajax have won the Champions League title four times in their history, and their pedigree will be put into test against Real Madrid when the knock out stage game begins.
Atletico Madrid v Juventus
This will be another tough game in the Champions League knock out stage as current Europa League champions will face Italian giants Juventus for a place in the last eight.
Juventus will be expecting Cristiano Ronaldo to be at his top form in this game, while Atletico will hope Antoine Griezmann and Diego Costa remain fit for the two encounters.
Liverpool v Bayern Munich
Bayern Munich finished as leaders in group E with 14 points, while Liverpool ended second in group C with nine points.
Liverpool will have to be at the top of their game against German side Bayern Munich who did not lose any game in the group stage and also conceded only five goals in six games.
Manchester United v Paris-Saint-Germain
Manchester United have not won the Champions League title since they lifted the cup last in 2007/08 season, and this will be a chance for United manager manager Jose Mourinho to prove his credential.
The Red Devils finished second in group H with 10 points, while Paris-Saint-Germain ended in first position in group C with 11 points.
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